Publications

2015

Yu FL, Lu J, Liu XM,Gazave E,Chang D, Raj S, Hunter-Zinck H,Blekhman R,Arbiza L, Hout C, Morrison A, Johnson AD, Bis J, Cupples LA,Psaty BM,Muzny D,Yu J, Gibbs RA, Keinan A, Clark G, Boerwinkle E (2015) Population genomics analyses of 962 whole genomes of humans reveal natural selection in non-coding regions Plos One: DOI: 10.1371

Zhang XY , Zhu Y, Liu XD, Hong XY, Xu Y, Zhu P, Shen Y, Ji YS, Wen X, Zhang C, Zhao Q, Wang YC, Lu J, Guo HW (2015) Suppression of endogenous gene silencing by degradation of normal cytoplasmic RNA in Arabidopsis Science: 348: 120-123

2014

Ye KX, Lu J, Ma F, Keinan A,Gu ZL (2014) Extensive Pathogenicity of Mitochondrial Heteroplasmy in Healthy Human Individuals Proceedings of the National Academy of Sciences of the United States of America: 111: 10654-10659

2013

Kaixiong Ye, Jian Lu, Srilakshmi Madhura Raj andZhenglong Gu (2013) Human expression QTLs are enriched in signals of environmental adaptation Genome Biology and Evolution: evt124

2012

Lu J, Clark AG (2012) Impact of microRNA regulation on variationin human gene expression. Genome Research 22: 1243-1254

2011

Zhou RC, Ling SP, Zhao WM, Osada N, Chen SF, Zhang M, He ZW, Bao H, Zhong CR, Zhang B, Lu XM, Turissini D, Duke NC, Lu J, Shi SH, Wu CI (2011) Population genetics in non-model organisms: II. Natural selection in marginal habitats revealed by deep sequencing on dual platforms. Molecular Biology and Evolution doi: 10.1093 (Lu J is a co-corresponding author)

2010

Lu J, Clark AG (2010) Population dynamics of PIWI-interacting RNAs (piRNAs) and their targets in Drosophila. Genome Research 20: 212-227

Tang T, Kumar S, Shen Y, Lu J, Wu ML, Shi S, Li WH, Wu CI (2010) Adverse interactions between micro-RNAs and target genes from different species. PNAS 107: 12935-12940

2008

Lu J, Shen Y,Wu QF, Kumar S, He B, Carthew RW, Wang SM, Wu CI (2008) The birth and death of microRNA genes in Drosophila. Nature Genetics 40: 351-355

Lu J, Fu Y, Kumar S, Shen Y, Zeng K, Xu A, Carthew RW, Wu CI (2008) Adaptive evolution of newly emerged micro-RNA genes in Drosophila. Molecular Biology and Evolution 25: 929-938

Wang HY, Fu Y, McPeek MS, Lu X, Nuzhdin S, Xu A, Lu J, Wu ML, Wu CI (2008) Complex genetic interactions underlying expression differences between Drosophila races: analysis of chromosome substitutions. PNAS 105: 6362-6367

2007

Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA et al (2007) Evolution of genes and genomes on the Drosophila phylogeny. Nature 450: 203-218 (Lu J is a coauthor of this paper)

Shapiro JA, Huang W, Zhang C, Hubisz MJ, Lu J, Turissini DA, Fang S, Wang HY, Hudson RR, Nielsen R, Chen Z, Wu CI (2007) Adaptive Genic Evolution in the Drosophila Genomes. PNAS 104: 2271-2276

2006

Tang T, Lu J, Huang J, He J, McCouch SR, Purugganan MD, Shi SH, Wu CI (2006) Genomic variation in rice - Genesis of highly polymorphic linkage blocks during domestication. PLoS Genetics 2(11):e199 (Tang T and Lu J equally contribute to the paper)

Lu J, Tang T, Tang H, Huang JZ, Shi SH, Wu CI (2006) The accumulation of deleterious mutations in rice genomes: a hypothesis on the cost of domestication. Trends in Genetics 22: 126-131 (Lu J and Tang T equally contribute to the paper)

2005 and before

Lu J, Wu CI (2005) Weak selection revealed by the whole-genome comparison of the X chromosome and autosomes of human and chimpanzee. PNAS 102: 4063-4067

Tang H, Wyckoff GJ, Lu J, Wu CI (2004) A universal evolutionary index for amino acid changes. Molecular Biology and Evolution 21: 1548-1556

Lu J, Li WH, Wu CI (2003) Comment on "Chromosomal speciation and molecular divergence-accelerated evolution in rearranged chromosomes". Science 302: 988